Tampilkan postingan dengan label keloid scar. Tampilkan semua postingan
Tampilkan postingan dengan label keloid scar. Tampilkan semua postingan

Minggu, 12 September 2010

Pulsed Dye Laser Treatment of Scars

Much of the research relating to the effects of the PDL on scars has been led by Dr Tina Alster in Washington, DC. She noted (Alster et al, 1993) that the PDL was able to alter argon laser-induced scars, which are often erythematous and hypertrophic. By using optical profilometry measurements she demonstrated a trend toward more normal skin texture as well as reduction in observed erythema. This work was extended to the treatment of erythematous and hypertrophic scars (Alster and Williams, 1995) using objective measurements; clinical appearance (colour and height), surface texture, skin pliability and pruritus could all be improved.

It is not known how the PDL improves the appearance of hypertrophic and keloidal scars. Microvascular damage may effect collagen or collagenase activity within the scar. Thermal damage to abnormal collagen within the hypertrophic scar may allow remodelling, and reduction in endothelial cell volume can affect type V collagen, which is increased in hypertrophic scars (Hering et al, 1983). Mast cell alterations after laser irradiation may also be of importance.

Although established hypertrophic scars can respond to treatment, early treatment of scars within the first months might prevent hypertrophy in individuals who are keloid-prone. I have certainly seen the benefits of early PDL treatment of excised recurrent keloids (Smith, Lanigan and Murison, unpublished observations). In a group of 11 patients treated in this way, none had a recurrent keloidal scar. Treatment at 6.5-7.5Jcm2 with a 5mm spot or 6-6.75Jcm2 with a 7mm spot is usually used. Treatment is repeated at 6- to 8- weekly intervals depending on clinical response. Keloidal scars require multiple treatments and the response is unpredictable. There may be additional benefits from using newer PDL with wavelengths of 590 or 595 nm but there is no published work to confirm this.

Alster's work has been confirmed by Dierickx et al (1995), who treated 15 patients with erythematous/hypertrophic scars and obtained an average improvement of 77% after an average of 1.8 treatments. Goldman and Fitzpatrick (1995) also treated 48 patients with similar laser parameters. Scars less than 1 year old did better than those more than 1 year old and facial scars did better there was an 88% average improvements, with total resolution in 20% after 4.4 treatments. Similar results were also seen in erythematous and hypertrophic facial acne scars by Alster and McMeekin (1996). Combinations of CO2­ and PDL treatment of hypertrophic non-erythematous scars have also shown additional benefit of the PDL compared to the CO2 laser alone (Alster et al, 1998).

For persistent scars combinations of intralesional corticosteroid injections, steroid impregnated tapes and laser therapy may be necessary (Sawcer et al, 1998).

More recent work by Manuskiatti et al (2001) showed improvement in scarring following treatment with the pulsed dye laser at varying fluences of 3, 5 and 7 Jcm-2. There was a trend for lower fluences to show most improvement and multiple treatments were required.

Two studies have compared the effects of pulsed dye laser treatment with other treatment modalities, particularly intralesional steroids. Alster (2003) compared pulsed dye laser treatment alone with laser therapy combined with intralesional corticosteroid treatment. Both treatment arms produced improvement in scars and there was no significant difference between the two treatments. Manuskiatti and Fitzpatrick (2002) compared scar treatment with intralesional corticosteroids alone or combined with 5-fluorouracil or 5-fluorouracil alone or the pulsed dye laser using fluences of 5 Jcm-2. All treatment areas were improved compared to baseline, there was no significant difference in treatment outcome compared to method of treatment. The highest risk of adverse sequelae occurred in the corticosteroid intralesional group. They concluded that treatment with intralesional corticosteroid alone or in combination with 5-fluorouracil or 5-fluorouracil alone and pulsed dye laser treatment are comparable.

Other studies however, have failed to demonstrate substantial effects of the pulsed dye laser on scars (Allison et al 2003; Paquet 2001; Whittenberg et al 1999;). Paquet assessed laser treated scars using remittance spectroscopy. Although a discrete decrease in redness of the scars was reported clinically this was not confirmed by objective data. Whittenberg et al, in a prospective single blind randomized controlled study compared laser treatment with silicon gel sheeting and controls. Although there was an overall reduction in blood volume and flow and scar pruritis over time, there were no differences detected between the treatment arms and the control groups. Allison et al, treating old and new scars with the pulsed dye laser with fluences of 5 to 6 Jcm-2 were unable to demonstrate any statistical differences between treatment and control by photographic assessments nor surface profile measurements. However, they did notice a significant improvement in scar pruritis in the active group compared with the controlled group.

In conclusion, there are now multiple studies assessing the effects of the pulsed dye laser in the treatment of scars. Although results are conflicting, particularly when controlled studies are performed, it would appear that in some cases laser therapy can be beneficial in the treatment for scars. It is likely that redness and pruritis are the two parameters that are most likely to significantly improve with this treatment.

source: ezinearticles.com

Kamis, 12 Agustus 2010

Types of Scars From Burns

An Overview

When a person suffers a burn, there are three types of scars which can emerge: Keloid, Hypertrophic, and Contractures. Keloid scars result from an overgrowth of scar tissue. The scars are generally red or pink in coloring but turn brown with time. Hypertrophic scars are raise, red, and thick. They differ from Keloid scars as they do not extend beyond the site of injury. Contracture scars emerge from a tightening of skin. These scars can affect the underlying tendons and muscles limiting mobility as well as causing nerve damage.

Keloid Scars

A Keloid scar involves a growth of excessive scar tissue beyond the site of the burn injury. It is caused when the body continues to produce collagen even after the wound has healed. These scars are very thick, ridged, nodular and itchy during formation. If the scar becomes too extensive it may limit mobility. Keloid scars are sensitive to friction such as clothing rubbing against them. People with darker skin and a youthful age are most likely to develop Keloids.

They can be minimized through cyrotherapy (freezing), cortisone injections, external pressure, steroid injections, radiation, or surgical removal. Generally, injections and external pressure are attempted first and if unsuccessful, outpatient surgery is performed under a local anesthesia. Doctors may recommend pressure garments to be worn to prevent Keloids from re-occurring. Treatments may be needed every few years as Keloids commonly reappear.

Hypertrophic Scars

Hypertrophic scars are limited to the site of injury and will improve over time. With the assistance of steroids, the healing process can be expedited.

Contractures

A contracture scar occurs when the skin tightens permanently. This can limit mobility as well as cause nerve damage. The scar develops when normal elastic tissues are replaced by inelastic fibrous tissue. This new tissue is resistant to stretching and inhibits normal movement.

Physical therapy combined with pressure and exercise can be helpful in aiding these scars. If therapeutic treatment does not succeed, surgery may be needed. A skin graft of flap procedure may be performed by a doctor. In addition, there are new techniques such as Z-plasty or tissue expansion which may be recommended.

source: ezinearticles.com

What Are Your Options For Keloid Scar Removal

Keloid scars can form for a variety of reasons. Acne and piercings are the most common causes of these unsightly raised scars, but there are others as well. Keloid scar treatment can be a little tricky, because you want to remove the scars without causing permanent damage or causing more to form. The treatment options below will present you with a few of the available options if you suffer from this type of scarring.

Injections

One common keloid scar treatment is to inject cortisone into the affected area. This is a slightly painful procedure, where an injection of a steroid is placed into the keloid until it has flattened. However, this treatment can actually cause the scar to be more noticeable and red, as the steroids can stimulate the formation of additional blood vessels near the top of the skin. This is a completely safe method that has been shown to produce guaranteed results.

Laser Treatments

The most popular keloids scar treatment on the market right now is laser procedures. Unlike injections, they do not redden the scars and make them more noticeable, and it is also completely safe. This method uses a laser to target the scars to flatten them and reduce redness. This process will also require several different treatments in order to be completely effective, and some minor discomfort may be involved as well.

Surgery

This is an option that is not advised by many doctors anymore, as the removal of keloids is a very tricky process that could cause many problems if done incorrectly. If not done properly, even more scars could appear in place of the one that was removed. There is also a high cost, risks, and pain associated with this method as well.

The options above are just a few of the keloid scar treatments that are available. If you suffer from these scars, then you will need to investigate all of the available options before making a final decision.

source: ezinearticles.com

What is the Best Treatment to Keloid Scar?

Keloid scar is a form of broken skin, a raised scar which extends outside of the discrete scar. It's often happened as a result of accident, surgery or more commonly from skin piercing. Keloid removal is part of the remedy to scar tissue removal.

Essentially the most generally recognized remedies to Keloid removal may be listed such as: steroid injection, interferon injection, surgery operation, laser treatment, silicone sheets dressing and Cryotheraphy. Nevertheless, amongst all the mentioned methods in treating Keloid scar, the very best combination would be laser surgery and the use of silicone scar sheets.

Although laser scar removal may be expensive, it's recognized to have the best result, the fastest removal time and the shortest healing period. Laser scar treatment makes use of laser to take away the layer of Keloid scar from our skin, once this surgical procedure is completed; we are able to proceed to use the silicone sheets dressing onto the treated area.

Today, silicone is being produced cheaply; additionally it is effective and popular among people who deal with Keloid scar. Silicone sheets or gel for Keloid treatment are to flatten the tissue and fade the color of the Keloid. One other benefit of Silicone is that it is extremely effective in stopping water, wind and other irritants from getting into the wound. It not only smoothes the tissue but also helps keep moisturizing it so to encourage the wound to heal.

Due to this fact, for the most effective treatment to Keloid removal, the combination of laser scar treatment along with silicone sheets dressing are the best way to get rid of Keloid scar.

source: ezinearticles.com

Kamis, 29 Juli 2010

Keloid Scar Removal

Keloid scars are basically a mass of collagen formed on the skin, when the healing process of a wound is interrupted. These interruptions could be formation of excess collagen or too little collagen. When there is excess collagen deposition at these places, the collagen grows in a very abrupt and irregular manner, totally asymmetrical with the skin surface, causing formation of scars. Keloid scars appear reddish-purple in color and are firm. People who develop these scars, initially use various home remedies and over the counter creams to get rid of them. However, most of these methods turn out to be ineffective. There are better methods for keloid scar removal, which effectively help in wiping out the scars.

Keloid Scar Treatment

Surgery
The keloid scar removal surgery could be a little risky, as it can cause a larger keloid formation. To avoid this, a few surgeons inject steroids, provide radiation or dress the wound with pressure dressings after cutting the keloid scar.

Laser treatment
Laser treatment is considered as an effective method for removal of keloid scar. In this treatment, the laser is made to move above the scar. This procedure vaporizes the top layer of skin and reveals the underneath layer, which is mare natural in appearance. Certain potent lasers have the ability to penetrate and destroy even lower layers of skin, thus stimulating growth of new collagen and getting rid of scars completely. The laser treatment takes around half an hour and is carried out under local anesthesia.

Cortisone Injections
The cortisone injections, also known as intralesional steroids, are given to the patient once a month, until the doctor feels that the purpose is served. Cortisone injections are not known to cause pain and are also considered safe. The injections aid in flattening out the keloids, so that the scar vanishes. There are chances though, that steroid injections may help in the formation extra superficial blood vessels, which need further treatment. It has been observed among people who have been through this treatment, that certain distinct marks remain on the skin which refuse to go away and require laser surgery.

Cryotherapy
Cryotherapy or cold therapy, is another way to remove keloid scars. In this process, keloids are flattened out by freezing them. The most commonly used freezing agent to perform cryotherapy is liquid nitrogen. The skin does get dark at places where this therapy is carried out.

Silicone Sheets
There is no guarantee of success in removing keloid scars using silicone sheets. To remove keloid scars using silicone sheets, the patient is made to wear silicone gel on the scar everyday for a substantial number of weeks, which is difficult to carry out. Doctors have found some other materials which can be used for dressing other than silicone and are equally effective.

Interferon
The human body's immune system produces various proteins to counter harmful viruses and bacteria. Interferon is one such protein. Research has proved that these proteins are capable of reducing keloids. The only aspect doctors are unsure about is, how long will its effect last. An alternative of this method could be applying aldara, a medicine to cure skin disorders, which stimulates production of interferon in the body.

Other methods of keloid scar removal include, injecting a chemotherapy agent fluorouracil and the use of radiation heat. Both these methods often need to be coupled with laser treatment to get optimum results.

Keloid Scar Removal: After Care

The doctor normally advises to wash the treated area softly with soap water. Wipe it off with a dry, soft towel and apply an antibiotic cream as suggested by the doctor. Doctors also prescribe certain oral antibiotics to prevent any infection. There are certain creams available which help to fade away the scar post-treatment, which can be used after the doctor's consent. It takes about 4 days for the skin regeneration process to start after treatment. The recovery period lasts for a couple of weeks at least and regular visits to the doctor is recommended during this period to ensure a smooth and quick recovery.

Keloid scar removal is simple, does not have any major complications and the recovery is also quick. There are a few things which need to be taken into consideration before selecting a keloid scar removal treatment. The cost factor, reactions to certain medications, previous instances of laser therapy used, are certain factors which need to be discussed with a dermatologist, before undergoing any treatment procedure.

source: buzzle.com

Senin, 12 April 2010

Which Type of Keloid Scar Treatment Really Works?

Keloid scars are part of the Hypertrophic group of scars in that they have the ability to expand in size. However, Keloids are a very unique type of scar as they are the only kind of wound which can expand beyond the original boundary of the injury. This means that a simple piercing from an earring can result in an over-sized Keloid that expands well beyond the ear.

Unfortunately, while these types of scars are considered abnormal and are less common than "normal" scars, they can still result from just about anything including a scrape, small cut, or even as the result of a common disease such as acne or chickenpox.

After A Keloid Develops...What Next?

After this type of wound develops, you do have options including using a topical Keloid scar treatment such as a silicone scar cream or gel. This is the most common type of treatment as these products are available without a prescription. Some extremely large Keloids may require surgery. However, surgically removing a Keloid results in the development of another Keloid around 50% of the time which is why surgery is reserved for only the most serious forms of Keloids.

There is also the option of injection therapy, but again this is reserved for extremely serious wounds. Typically, skin and health care professionals suggest using a silicone based treatment due to the fact that this method has been clinically shown to diminish both the size and color of Keloids. While you may purchase silicone scar sheeting, many consumers prefer to use a gel based product as this option is not only generally more cost effective, but it also allows the scar to remain completely protected during movement.

source: ezinearticles.com

Boxcar, Ice Pick, Hypertrophic & Keloid Scarring

Acne is something almost everyone has to deal with once in their life, either as a teenager or believe it or not as an adult. The most horrible thing about acne is that it can leave your skin with different types of scarring. Boxcar, ice pick, hypertrophic and keloid scars are some reminders left by acne.

Types of Scars

Ice Pick Scars. These are characterized by deep pits in your skin. These are the most common type of scarring left from acne.

Box Car Scars. These are similar to ice pick scars but are angular scars that usually occur on the temple and cheeks. These scars can be either superficial or deep and are very similar to chicken pox scars.

Hypertrophic Scars. These are raised scars caused by the overproduction of collagen. They can be easily recognized by the raised, hard tissue after the skin has healed.

Keloid Scars. Keloid are similar or a form of hypertrophic scarring but a keloid occurs when the scar tissue grows beyond the borders of the initial wound.

Acne Scar Removal and Prevention

The best way to prevent acne scars is to keep your acne controlled with an acne treatment cream. Which creams work best depends on your type of skin, but natural skin care products are the best form to protect your skin from breakouts. Natural products are a good alternative because they do not cause any secondary effects like chemically based products that can irritate your condition instead of controlling your breakouts.

If you already have acne scars and are looking for a treatment that will get rid of those reminders, the best way to go is to try a home microdermabrasion cream. By gently exfoliating the very top layer of the skin, to gradually remove scarred or discolored epidermal tissue. Home microdermabrasion products are great for boxcar scars or ice pick scars, but they are not recommended for raised scars as those types of scarring can be more sensitive.

For raised scars, a cream that contains the secretion of the land snail Helix Aspersa Muller is a great option. The snail secretion has properties to control collagen production, in other words, stop the growth of raised scars. It has also been known to reduce the size of both old and new keloid scars without irritating the skin.

The best way to prevent acne scarring is to control your acne before it damages your skin. If you have those unsightly reminders, use a home microdermabrasion product or a natural skin care cream that contains the secretion of the land snail Helix Aspera Muller to gradually eliminate your acne scars.

source: ezinearticles.com

Hypertrophic & Keloid Scar Removal

Hypertrophic Scars

Hypertrophic scars grow indefinitely but they are restricted to the site of the wound. They form due to the overproduction of collagen which is what makes the scar raise. It's usually pink or flesh colored and occurs mostly on the chest, back, shoulders and ear lobes. They can be caused by a number of factors which include burns, insect bites, injections and/or tattoos. However, the formation seems to be caused by a hereditary factor.

Keloids

Keloids are formed after the skin has gone through some kind of trauma. The body attempts to heal the lesion by generating collagen, but people who are prone to keloids create too much of this substance. This causes the scars to grow past the limit of the wound. Keloids are basically characterized by that they don't know when to stop.

Keloids are pink, brown, purple or flesh colored and are irregularly shaped. They tend to grow progressively and they unfortunately do not subside. Keloids can be especially difficult to have because they can be very tender to the touch and itchy.

How to Treat Raised Scars

Both imperfections are very difficult to eliminate. Nevertheless, there are some scar removal options:

Laser Therapy: One of the most effective ways to remove hypertrophic and keloid scars is by undergoing laser therapy. The procedure peels off its top layer to encourage proper healing.

Steroid Injections: This treatment is normally used when the scar is just beginning to grow. It prevents it from raising beyond what it should. It may also reduce the size of preexisting marks. Nevertheless, these injections are quite painful and require anesthesia.

Surgery: You may choose to get rid of keloid or hypertrophic scars by undergoing surgery. It's often followed by compression therapy to prevent the scar from rising. Unfortunately, in most cases a raised scar will replace the old keloid, albeit in a smaller size.

source: ezinearticles.com

Kamis, 11 Maret 2010

Silicone Scarless Healing

There are several types of scars, and several treatment options you can choose from. For the most part, scars can be treated without too much trouble, although keloid scars are quite possibly the most difficult lesions to get rid of because they usually recur.

Keloids are abnormal tissue that extends beyond the area of the initial wound. It's very common for them to keep growing and that's why it is important that you treat them as soon as possible. Keloid scars can be caused by piercings, cuts, and even acne. Keloidal acne scarring is especially devastating because an acne breakout can affect large areas of the face, neck, chest and back. To prevent any kind of acne scar (hypertrophic, atrophic and keloidal) it is important to follow a regular cleansing routine that includes an acne cream.

But, how can you treat scars that keep growing and have a high recurrence rate? Luckily, there are treatment options. These alternatives include a combination of surgery, intralesional corticosteroids, silicone bandages and compression therapy. Surgical excision is quite straightforward. The doctor will study the scar and then decide if to inject corticosteroids into the scar before, during or after surgery to help reduce the chances of recurrence. After surgery, the person will probably be fitted for compression devices.

Compression devices and silicone bandages have shown excellent results with keloid scars. This may be an effective scar treatment because it exerts constant pressure on the wound and keeps it from growing. Doctors are not exactly sure how they work, but studies have shown that compression reduces the production of collagen.

If you are fitted for a compression device you may have to use it for several months or a year before the doctor will allow you to remove it. These devices include garments (gloves, body suits and masks) that must be worn 24 hours a day to produce the desired effects. They may also include zippers or special linings to make their use more comfortable and convenient.

Silicone bandages are often used to achieve scar less healing. They, just as with compression garments, exert pressure for extended periods of time. Silicone bandages can be worn up to 9 hours a day, for several months. These bandages are also hermetic and come in an easy-to-use format. Once you are done using them, you simply discard them. Some people find this format more convenient than pressure garments. Bandages and compression garments can be used to help prevent and treat keloid scars. They are often used to treat smaller keloid scars.

Scars

A scar isn't so bad if it's small or in a location that's easy to conceal. But often you want a way to treat those scars other than hiding them under clothing. The truth is this: The scar will never completely go away, but there are some methods that can help reduce its size and appearance.

Scar formation is a natural part of the healing process after injury. Various factors influence how your skin scars. Of course, the depth and size of the wound or incision and the location of the injury are going to impact the scar's characteristics. But your age, heredity, even your sex or ethnicity, will all affect how your skin reacts.

These are several different types of scars including:
Keloid scars. These scars are the result of an overly aggressive healing process. These scars extend beyond the original injury. Over time, a keloid scar may affect mobility. Possible treatments include surgical removal, or injections with steroids. Smaller keloids can be treated using cryotherapy (freezing therapy using liquid nitrogen). You can also prevent keloid formation by using pressure treatment or gel pads with silicone when you sustain an injury. Keloid scars most often occur in Blacks.

Contracture scars. If your skin has been burned, you may have a contracture scar, which causes tightening of skin that can impair your ability to move; additionally, this type of scar may go deeper to affect muscles and nerves.

Hypertrophic scars. Raised and red scars that are similar to keloids, but do not breach the boundaries of the injury site. Possible treatments can include injections of steroids to reduce inflammation.

Acne scars. If you've had severe acne, you probably have the scars to prove it. There are many types of acne scars, ranging from deep pits to scars that are angular or wavelike in appearance. Possible treatments will depend on the types of acne scars you have.

Minggu, 07 Maret 2010

Types of Scars

Keloid scars
Keloids are itchy clusters of scar tissue that grow beyond the edges of the wound or incision. They occur when the body continues to produce the tough, fibrous protein known as collagen after a wound has healed. They are more common in dark-skinned people. Keloids are treated by injecting a steroid medication directly into the scar tissue to reduce redness and itching. However, the disheartening fact is that keloids have a tendency to recur, sometimes even larger than before, thus requiring repeated procedures.

Hypertrophic scars
These scars, unlike keloids, remain within the limits of the original wound. They often improve on their own, though it may take a year or more. They may also require steroid applications or in some cases may have to be improved surgically.

Contractures
Burns or other injuries that result in the loss of a large area of skin may form a scar that pulls the edges of the skin together, a process called contraction. Improving a contracture usually involves cutting out the scar and replacing it with a skin graft or a flap. In some cases, a procedure known as Z-plasty may be used.

Facial scars
Mostly, facial scars are cut out and closed with tiny stitches, leaving a less noticeable scar. Some facial scars can be softened using a technique called dermabrasion, that leaves a smoother surface to the skin, but does not completely erase the scar.

Laser Scar Removal

The wound-healing process begins with inflammation, progresses to tissue formation and ends with modifying specific factors in the anatomy – such as collagen, the main protein found in connective tissue that supports the skin, bone, cartilage and blood vessels. Scarring occurs when the wound-healing process is disrupted by certain factors such as too much or too little collagen. For example, a keloid scar is a mass of collagen.

Today's laser scar removal techniques can reduce the appearance of several types of scars, including Keloid Scarring, Hypertrophic Scarring and Atrophic Scarring. like pockets in the skin that can result from skin conditions or diseases such as acne. Not everyone is a candidate for laser scar removal. People with skin disorders such as psoriasis, cystic acne and dermatitis may not be ideal candidates. Those using certain medications such as isotretinoin for acne must stop using the medication for six months prior to the procedure.

During laser scar removal, the laser is moved along the scar. This can vaporize or remove a layer of skin and expose a more natural-looking skin layer, which heals over time to minimize scar appearance. Other lasers may target lower layers of the skin, stimulating new collagen growth and correcting scars from the inside out. The laser scar removal procedure is often performed under local anesthesia in an outpatient surgery center, surgeon's office or hospital. Sometimes, general anesthesia is used. The surgery takes anywhere from a few minutes to an hour and a half.

Many types of lasers are available, each of which has unique benefits for scar removal. The CO2 and Er:YAG lasers are best suited for acne scarring. The CO2 is an ablative laser that basically sandblasts the skin away; resulting in some substantial downtime. The Er:Yag is also ablative, but less so than the CO2; meaning that it is less damaging. Many different companies manufacture CO2 and Er:YAG lasers.

Fractionated CO2 and Er:YAG lasers including the Fraxel and fractionated radiofrequency treatments also are very helpful for acne scarring, but they require multiple treatments. Fractionated lasers work by treating a fraction of the skin's surface. These lasers create tiny wounds in the deeper layer of the skin. Each wound is surrounded by untreated skin, helping to repair the treated area via a controlled wound-healing process. Both CO2 and Erbium YAG lasers as well as radiofrequency treatments can be fractionated.

Until recently, African-Americans were not considered ideal candidates for laser scar removal, but times are changing. Certain lasers (such as fractionated infrared lasers) and radiofrequency devices such as Thermage may be helpful in treating acne scars among African-Americans. There is still little that lasers can do to treat keloid scars affecting this population.

Rabu, 03 Maret 2010

Treatment of keloid scars

No effective treatment exists for permanent keloid removal. When applied to excised-sites, imiquimod 5% cream reduces keloid recurrence. Case series suggest the tolerability and efficacy of imiquimod 5% application to sites of shaved keloids; however, this has not been verified in placebo-controlled studies. To determine the tolerability and compare the efficacy of imiquimod 5% and vehicle cream in lowering keloid recurrence after shaving.

Twenty randomized, shaved keloids were administered imiquimod 5% or vehicle cream nightly for two weeks, and then given three times a week under occlusion for one month. Pain, tenderness, pruritus and keloid recurrence were evaluated at baseline, week 2, week 6 and 6 months. Tenderness and pain were significantly (p= 0.02 and p= 0.02, respectively) higher at week 2 in the imiquimod group than for those treated with vehicle cream. Pruritus did not attain statistical difference between the groups.

Conclusion: Imiquimod was well tolerated. There was not enough statistical power to detect a significant difference in six-month keloid recurrence rates between the two treated groups. At the present time, there is no therapeutic modality that is 100% safe and effective for the treatment of keloid scars. Recurrence rates for surgical excision of keloids have been reported between 45% and 100%. Keloids represent an abnormal response to injury where the healing environment manifests low levels of interferon alpha and gamma, in addition to other abnormalities. Furthermore, interferon alpha 2b has been shown to be anti-fibrotic by normalizing collagen and glycosaminoglycan production and collagenase activity.

Prior uncontrolled studies have suggested imiquimod 5% cream may be a useful adjuctive treatment to surgery. In an uncontrolled study by Stashower, eight keloids were debulked by tangential shaving and imiquimod cream applied daily for six weeks with no recurrences at one year. In another uncontrolled, pilot study, eight keloids were treated with imiquimod 5% cream daily for 8 weeks. At 24 weeks, 25% (2/8) recurred and imiquimod was relatively well-tolerated. This purpose of this study was twofold: first, to objectively examine the tolerability of treating newly tangentially shaved keloids with imiquimod 5% cream and, second, to evaluate the efficacy in lowering the recurrence rates of keloids.

Minggu, 21 Februari 2010

The answer for scars and wrinkles

Some degree of scarring appears when wounds heal, and this is a natural part of healing process. There are two types of scars, hypertrophic and keloid scars. Keloid scars are a more serious form of scarring, as they grow indefinitely into large tumors. Scar treatments can be done either by cosmetic surgery or by non-surgical options, such as scar gels, crème, and adhesive silicone sheeting. Intensive researches, for non-surgical scar treatment and scar reduction using scar gels and crèmes, are being carried out by medical industries.

Wrinkles are worse than scars because wrinkles appear all over the skin affecting the person both physically and psychologically. Factors like habitual facial expressions, aging, loss of facial fat, sun damage, smoking, poor hydration, and even gravity contributes in the formation of wrinkles. Although there are several kinds of treatments, such as chemical peels, dermabrasion, laser resurfacing, non-ablative laser resurfacing, and plastic surgical procedures, anti-aging serum and crèmes are the safest and cheapest means to get rid of wrinkles.

Based on latest technology, Scarheal Inc has produced superior scar gels for non-surgical scar reduction treatments and anti-aging serum and cremes for skin rejuvenation and wrinkle treatment. Scar Esthetique creme, Scar Fx (self-adhesive silicone sheeting), and Rejuvaskin (anti-aging serum) are wonder working products produced by Scarheal Inc. Scar Esthetique is the only product in the market that has a combination of anti-oxidants, cortisone, vitamin E, and onion extract. Scar treatment is effective on your most severe scars, which include Hypertrophic and Keloid scars. It is a low-cost, non-surgical scar treatment that neutralizes the scar's color and works to flatten raised scars. The regular use of Rejuvaskin anti-aging serum rejuvenates your skin and prevents early aging by removing wrinkles on your skin.

Senin, 15 Februari 2010

Red scars

Most scars will be red during the healing phase and in most cases this will fade spontaneously. Persistent redness in scars may respond to Candela V-beam™ laser treatment, the same laser used to remove blood vessel blemishes and birthmarks.

Some people have a tendency to develop brown pigmentation in areas of damaged skin. It is usually transient but if it persists beyond nine months, treatment with the Q-Switched YAG laser or the Q-switched Ruby laser may help fade the pigmentation. Treatment with a prescription "fading" cream such as Hydroquinone 3% may be helpful.
Raised (hypertrophic) scars and keloid scars. In extreme cases, scar tissue may "over grow" causing thickened, raised scarring. This condition is known as hypertrophic scarring. It will usually settle spontaneously over 12 months. This improvement can be accelerated with treatment. Unfortunately, in some individuals, these changes do not settle and treatment may be required.

In some people this scarring reaction is so severe that even a scratched mosquito bite results in a thick scar. People who are prone to this type of "over healing" are usually aware of the problem and this is one situation where early intervention is appropriate. After taking a history and inspecting other scars, a dermatologist is able to abort the over growth of scar tissue with regular micro-injections of cortisone solution. If the problem is not identified until after scar formation, the tissue may still respond to micro-injection treatment. Silicone sheeting designed to flatten scars may also have a role in the treatment of raised scars.

Keloid scars are a more severe problem and the tendency is often genetic. It is more common in darker skin types. The classic feature of keloid scarring is that it grows and invades beyond the site of the actual injury. It is also often exquisitely sensitive and prone to itching. Keloids scarring commonly occurs in acne scars on the chest and back. Treatment for keloid scarring is similar to that outlined for hypertrophic scarring. It also has the tendency to recur over the years and require repeated courses of treatment. People prone to keloid scarring should consider preventative treatment as early as possible following injury and avoid unnecessary surgery.

Treat unsightly acne scars

As if the unsightly appearance of acne pimples is not enough for all too many people once the pimples disappear they are left with frequently equally unsightly scarring. The first thing to realize is that some conditions which look very much like scars are not in fact scars at all but are macules and other bumps which can occur following acne treatment. The redness which often accompanies macules and other bumps can last for up to a year but this is not permanent and these are not true scars.

True scars are produced by the healing process itself (often resulting from the creation of fibrous tissue) and represent a permanent change to your skin tissue. Permanent scarring often results from the action of your white blood cells as they attack the bacteria which causes acne and this 'battle' can produce permanent changes to the underlying cells of your skin.

Such damage is not however just limited to the cells below the skin surface and you can be left with such things as so-called icepick scars which are small pinholes formed in the surface of the skin. They are called icepick scars because they look as if the skin has been attacked with an icepick and they are often quite deep and thus unresponsive to such things as dermabrasion and laser resurfacing treatment.

Another common form of acne scarring are boxcar scars, which are similar to icepick scars but tend to be flatter on the bottom instead of narrowing to a point as icepick scars do. Boxcar scars are shallower than icepick scars and can be treatment using skin resurfacing techniques. Finally, keloid scars, which tend to extend beyond the site of the original pimple injury, result from an excess production of collagen and are usually seen as a firm shiny pink or red scar.

In all cases the best way to avoid acne scars is to prevent then from developing in the first place but, where this has not proved to be effective, then there are several standard treatments including dermabrasion. Dermabrasion is a form of treatment used to treat a wide range of different skin conditions, including mild (and sometimes moderate} acne scarring. After the application of a local anesthetic, a high speed brush is used to remove layers of skin. In many cases, once the skin heals naturally, acne scar disappear altogether and, where this is not the case, they are usually very much less evident.

A commonly alternative to dermabrasion today is microdermabrasion in which, instead of using a high speed brush, aluminum oxide crystals are moved rapidly across the surface of the skin using a form of vacuum hose. This is a little bit like a form of medical 'sand blasting' and is less invasive than dermabrasion and causes less trauma to the skin. Microdermabrasion can be effective in cases of very mild acne scarring but generally does not produce as good results as are seen with dermabrasion.

Laser Treatments. For some people laser treatment (often using CO2 lasers) is particularly effective and mild scarring can sometimes be removed with just a single treatment. When in the hands of a trained professional a laser can be used to remove scar tissue, or to alter the size of scars and change the contour of the skin to make scars very much less visible. This is however a fairly harsh treatment which effectively works by burning the surface of the skin and so it can produce redness which will persist for several weeks.

Surgery. Surgery, using a technique known as 'punching' is often used to remove some icepick scars. An icepick scar is cut out down to the subcutaneous fat layer and the resulting hole is then repaired either using sutures or a small skin graft. Scars can also be repaired using subcisions which involve lifting the scar tissue away from unscarred skin. This technique can be effective but at the moment results using this technique have been somewhat mixed.

Drug Treatment. Keloid scars do not respond well to any of the treatments described so far and indeed they will usually stimulate the formation of more keloids and make matters worse. In this case therefore it is common to either apply a topical retinoid cream or to inject steroid-type drugs directly into the skin around the site of the scar. Unfortunately, keloid scars are difficult to treat and results vary widely from one individual to the next.

Perhaps the most important advice which anybody can be given when it comes to treating acne scars is that you should start by getting a proper diagnosis from a professional dermatologist. Your dermatologist will not only be able to advise you about the treatments available for your particular type of scarring, but will also be able to advise you about both the benefits and risks of each type of treatment.

Sabtu, 13 Februari 2010

Treatment for scars

Scars are usually the result of injuries. These are areas of fibrous tissue that usually replace the normal skin right after an injury. This is part of the healing process of the skin and part of the skin's action to repair itself. Every wound right after an accident with the exception of minor lesions will usually contribute scarring on the skin. The worse the damage on the skin, then the scar will be worse as well.

The scar on a person may form differently based on the location of the injury and the age of the person as well. Most of the time, the scar that can be seen on the skin will be flat and pale and will usually leave a trace to the original injury that caused them. Most of the time redness on the area will follow. This redness is not a scar and this isn't permanent. This will go away after some time. If there is a cut in the skin of the person, then the body of the person will react by laying new collagen fibers. This is what is referred to as the fortuna scar, a situation where in the body of the person can no longer rebuild the tissue exactly as it was. There are two more types of scars and these cars are due to the over production of collagen in the body.

The hypertrophic scar is usually seen as a raised lump of skin but doesn't usually grow too large. This scar will usually improve in appearance after some time. The keloid scar on the other hand is the more serious between the two scars. This type of scar can grow into large and tumurous growth. These two types of scars are usually common on the younger and darker-skinned people. These two scars are caused by surgery, accidents and can be caused by acne as well. Scars that can be seen on the skin of a person may take the form of a stretched skin. These scars are known as striae.

Once a scar presents itself on the skin of a person, then this scar can no longer be removed. And though there may be some treatments out there, traces will always be there. Some of the more popular treatment methods that are used now are the corticosteroid therapy, pressure garment therapy and silicone gel sheets that was introduced in 1980s. The uses of topical treatments are popular approaches in addressing scars. The silicone gel and the silicone gel sheets are often applied to the affected area of the skin.

These two are easier to use and offer lesser risks of side effects to the user if compared to surgical excision, injections, and pressure therapy and cryotherapy treatments. Pressure garments on the other hand are used with the supervision of a professional. Steroid injections can be taken as well and this can help flatten and soften the appearance of the keloid and the hypertrophic scars. Other popular treatments used now are dermabrasion, collagen injections, laser surgery and resurfacing, surgery, radiotherapy and the use of natural remedies.

Jumat, 12 Februari 2010

Keloids and hypertrophic scars

Keloids are raised, reddish nodules that develop at the site of an injury. After a wound has occurred to the skin both skin cells and connective tissue cells (fibroblasts) begin multiplying to repair the damage. A scar is made up of 'connective tissue', gristle-like fibers deposited in the skin by the fibroblasts to hold the wound closed. With keloids, the fibroblasts continue to multiply even after the wound is filled in. Thus keloids project above the surface of the skin and form large mounds of scar tissue.

Keloids may form on any part of the body, although the upper chest, shoulders and upper back are especially prone to keloid formation. Symptoms include pigmentation of the skin, itchiness, redness, unusual sensations and pain. It is estimated that keloids occur in about 10% of people. While most people never form keloids, others develop them after minor injuries, even insect bites or pimples. Darkly pigmented people seem to be more prone to forming keloids. Men and women are equally affected.

A hypertrophic scar looks similar to a keloid. Hypertrophic scars are more common. They don't get a big as keloids, and may fade with time. They occur in all racial groups. Keloids are considered a benign tumor, but they are mainly a cosmetic nuisance and never become malignant. Operating on a keloid usually stimulates more scar tissue to form, so people with keloids may have been told that there is nothing that can be done to get rid of them. Keloids may be often be prevented by using a pressure dressing, silicone gel pad or paper tape over the injury site. These are left on for 23 of 24 hours each day. This treatment is after healing of the wound or injury, usually within a month. Once they have formed, there is no completely satisfactory treatment for keloids. Treatments include cryosurgery (freezing), excision, laser, x-rays, and steroid injections.

The best initial treatment is to inject long-acting cortisone (steroid) into the keloid once a month. After several injections with cortisone, the keloid usually becomes less noticeable and flattens in three to six month's time. Hypertrophic scars often respond completely, but keloids and are notoriously difficult to treat, with recurrences commonly seen. People who have a family history of keloids have a higher rate of recurrence after treatment. Cryosurgery is an excellent treatment for keloids that are small and occur on lightly pigmented skin. It is often combined with monthly cortisone injections. Earlobe keloids are often surgically excised and followed with several steroid injections. In addition, a drug called alpha-interferon has been injected into the scar immediately after keloid removal with very promising results. Laser treatment is very good at improving skin texture and color, but doesn't always flatten out the keloid.

For severe cases, the keloid can surgically excised and given x-ray treatments to the site immediately afterwards, usually the on the same day. This works in about 85% of the most severe cases. Electron beam radiation can be used, which will not go deep enough to affect internal organs. Orthovoltage radiation is more penetrating and slightly more effective. There have not been any reports of this causing any form of cancer in many years of use, but it is very expensive. Silicone pads and creams are sold over the counter for use on keloids. These do benefit hypertrophic scars but will not cure a true keloid. However, they can reduce pain, swelling and itching from a keloid. They usually take 3 months or more to work.

Expecting after surgery

Collagen Injections The result is immediate. Pitted scars look smooth and even. However, these results are not permanent. Periodic treatments are necessary to maintain results. Dermabrasion After the procedure, the treated area may be covered with an ointment, a wet or waxy covering, and/or a dry covering. The skin may feel as though it is severely sunburned. Moving facial muscles and eating may be uncomfortable. Oral pain medication may be taken to ease the discomfort. In some cases, antibiotics may be taken in order to prevent possible infections. The skin is usually swollen for around 24 to 48 hours after the procedure. During this time, a scab begins to form over the treated area.

Vascular Laser The treated area may show purple discoloration, which should fade in 5 to 10 days. Generally after this period the scar should be less red and raised. Laser Skin Resurfacing You may experience some swelling and discomfort. Cold packs are usually recommended to reduce the swelling. If a bandage was applied after the surgery, it will be removed after approximately one week, and an ointment will then be applied. Some surgeons use a moisture retaining tape to bandage the treated area. Because this bandage must remain dry, you will not be able to shower until the bandages are removed.

If the treated area is not bandaged, you will need to wash the area several times every day. After each washing, you will need to apply an ointment, such as petroleum jelly, to the treated area. You will need to use caution in caring for the treated area. Scabs may form and last for about 10 days. If you are experiencing discomfort, an over-the-counter oral pain medication can be taken. Punch Grafting – The new skin is taped into place for about seven days to permit healing.

Skin Grafts and Flap Surgeries You can expect to feel some discomfort after facial scar revision surgery. Some swelling, bruising and redness are generally unavoidable. Any sutures will be removed within days after the surgery but your skin needs more time to heal. In general, surgeons suggest limiting activities -- especially any activity that places undue stress on the area of the incision. Silicone Gel Sheets After 2 to 12 months scars should look flatter and smoother. The procedure may have to be repeated after several years since keloid scars have the tendency to return.

Steroid Applications and Injections You may experience mild soreness, as with any injection. The scar should reduce in redness and thickness. The procedure may have to be repeated after several years since keloid scars have the tendency to return. Tissue Expansion Expect some fairly mild swelling and possible bruising. Stitches are normally removed within a week of the procedure. Z-plasty and Related Techniques The treated area will be closed with fine stitches, which will be removed within a week of the procedure. As with most incisions, the area may swell or bruise slightly.

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